Abubuwan da ke cikin kitse sun ƙunshi ƙwayoyin rigakafi waɗanda zasu iya haifar da haɓakar halayen kumburi, ciwon sukari da sauran cututtuka. Amma da farko abubuwa farko
Tsananin da'ira
Kamar yadda ka sani, nau'in ciwon sukari nau'in 2 yawanci yana tare da nauyin kiba. Ga wani irin mummunan yanayi. Saboda gaskiyar cewa kyallen takarda ta daina zuwa amsawa na insulin da kuma riƙe glucose, metabolism ya ɓace, wanda ke ɗaukar bayyanar ƙarin kilo.
A cikin mutane masu kiba, ana lalata ƙwayoyin kitse koyaushe, kuma ana maye gurbinsu da sababbi, a cikin lambobi mafi girma. A sakamakon haka, DNA kyauta na sel da suka mutu suna fitowa a cikin jini kuma matakin sukari ya tashi. Daga jini, DNA kyauta galibi yana shiga cikin sel na rigakafi, macrophages da ke yawo a cikin tsopose nama. Masana kimiyya daga Jami'ar Tokushima da Jami'ar Tokyo sun gano cewa a cikin martani ga tsarin na rigakafi, ana haifar da tsarin kumburi, wanda a kullun yana amfani da shi azaman makami a kan cututtukan cututtuka da kwayoyin cuta, kuma a kan babban adadin yana haifar da matsalolin metabolism kuma zai iya, musamman, haifar da ciwon sukari.
Labari mara kyau
Masu bincike daga Jami'ar California, San Diego sun gano cewa macrophages da aka riga aka ambata sun ɓoye ɓoyayyun - vesicles microscopic wanda ke aiki don musayar bayanai tsakanin sel. Exosomes yana dauke da microRNA - kwayoyin kwayoyi wadanda ke shafar kirar protein. Ya danganta da abin da microRNA za a karɓa a cikin “saƙo” ta tantanin ɓoyayyen, hanyoyin gudanar da aiki za su canza a ciki bisa ga bayanan da aka karɓa. Wasu exosomes - mai kumburi - suna shafar metabolism ta hanyar da ƙwayoyin suka zama insulin na iya tsayawa.
A lokacin gwajin, an sanya kwalliyar kayan kwalliya daga mice masu yawa a cikin dabbobi masu lafiya, kuma hankalinsu na insulin ya lalace. Sabanin haka, “kwastomomi” masu cike da koshin lafiya da aka yiwa dabbobi marassa lafiya sun dawo da maganin insulin.
Gobarar da aka samu
Idan za a iya gano wane microRNAs daga rikice-rikicen da ke haifar da ciwon sukari, likitoci za su sami “makasudin” ci gaban sababbin magunguna. Dangane da gwajin jini, wanda cikin sauki ne a ware miRNAs, zai yiwu a fayyace hadarin kamuwa da cutar sankarau a cikin wani mara lafiya, da kuma zabar wani magani da ya dace da shi. Irin wannan bincike zai iya maye gurbin biopsy mai raɗaɗi wanda aka yi amfani dashi don gano yanayin ƙwayar.
Masana ilimin kimiyya sunyi imanin cewa ƙarin nazarin miRNAs zai taimaka ba kawai don magance ciwon sukari ba, har ma da taimako na wasu rikicewar kiba.
