Kwayoyin cholesterol an gano su azaman magungunan mu'ujjiza na karni. Marasa lafiya da ko da ɗan ƙara tasirin cholesterol ne sau da yawa likitoci suna ƙarfafa su don fara shan ƙwayar statin.
Menene statins? Wadannan kwayoyi magungunan kwayoyi ne wadanda aka tsara don rage cholesterol. Statins suna aiki ne ta hanyar hana enzyme buƙatar don samar da cholesterol a cikin hanta. Idan ba tare da taimakon wannan enzyme ba, jikin ba zai iya juya mai ya zama cholesterol ba.
Yawan hauhawar cholesterol da ke yawo a cikin jijiya yana da haɗari saboda cholesterol yana son tarawa a bango na jijiyoyin bugun gini tare da haifar da tashe tashen ƙwayoyin cuta na atherosclerotic, wanda ke ƙara haɗarin haɗarin kamuwa da zuciya - bugun jini da bugun zuciya.
Akwai nau'ikan magunguna. Sun haɗa da manyan ƙarfin siffofin:
- Atorvastatin;
- Rosuvastatin;
- statins of matsakaici ƙarfi, wanda Simvastatin wakili ne.
Yawancin marasa lafiya suna ɗaukar waɗannan magungunan, suna tunanin cewa ta wannan hanyar za su hana ko rage jinkirin ci gaban atherosclerosis. Akwai ma shaidar farfaganda don ruwan sha mai tsafta.
Babu wata shakka cewa statins na iya rage cholesterol cikin sauri, amma tambayar ita ce ko duk marasa lafiya ya kamata suyi amfani da su, idan aka lura da mummunan tasirin wadannan kwayoyi.
Bayan haka, an gano cewa duk da cewa statins suna da tasirin rage tasirin cholesterol a cikin mutanen da ke fama da cututtukan zuciya, tasirin yana da karanci sosai bawai zai tabbatar da illolin da wadannan magungunan ke da shi ba.
Hatsarorin amfani da mutum-mutumi
Binciken da aka yi kwanan nan ya ba da rahoton cewa marasa lafiya da ke da nau'in ciwon sukari na 2 da kuma ci gaba na atherosclerosis waɗanda suka yi amfani da kowane statin sau da yawa suna da babban filin wasan jiyya fiye da marasa lafiyar da ba sa yin amfani da mutum-mutumi. A cikin rukunin mahalarta mahalarta waɗanda ba su shan magungunan ba, ƙimar da mahaifa ta atherosclerotic ta haɓaka yayin da suka fara shan magani. Yawancin mutane da suke daukar statins suna jure su sosai. Amma wasu mutane suna fuskantar sakamako masu illa, daga cikinsu mafi yawan su ne:
- Ciwon kai.
- Rashin damuwa da tashin hankali na bacci.
- Ciwon kirji, jin hankali, ko rauni (myalgia).
- Damuwa.
- Dizziness
- Ciwon ciki ko amai.
- Ciki na ciki ko zafi.
- Bloating da flatulence.
- Zawo gudawa.
- Maƙarƙashiya
- Rashes.
Sauran karatuttukan sun kuma yi maganin manyan sakamako masu illa, haɗe da masu zuwa:
- lalacewar hanta da ƙwayar ƙwayar cuta saboda karuwar adadin enzymes da ke faruwa sakamakon yawan wannan rukunin magunguna;
- lalacewar tsoka wanda zai iya haifar da asarar ƙwayoyin tsoka, gazawar koda, da mutuwa;
- increasedara yawan sukari na jini da haɗari mafi girma na ciwon sukari na 2;
- asarar ƙwaƙwalwar ajiya, damuwa, mantuwa (wanda zai iya zama amnesia) da sauran cututtukan da ke tattare da jijiyoyin jiki waɗanda aka lura su daina da zarar amfani da statins ya tsaya;
- lalatawar jima'i.
Idan mai haƙuri yana da wani haɗin gwiwa wanda ba a bayyana ba ko kuma ƙwayar tsoka, raunin hankali ko rauni yayin ɗaukar magani, ya kamata ka nemi likita nan da nan. Mata masu juna biyu ko marasa lafiya da ke da ƙwaƙwalwa ko cututtukan hanta yakamata su yi amfani da statins.
Dangane da wannan, likita ne kawai ya kamata ya tsara magunguna na wannan rukunin, tare da yin la'akari da kyau a kan duk halaye masu kyau da marasa kyau.
Ga marasa lafiya da yawa, har ma da cututtukan zuciya, babu buƙatar magani na wannan nau'in. A cikin wannan haɗin, duk duniya tana neman hanyoyi don rage cholesterol ba tare da statins.
Statin-free cholesterol ragewan
Wadanne magunguna ke rage cholesterol banda statins? Akwai wasu magunguna da yawa waɗanda ke da aikin rage ƙarfi na ƙwaƙwalwar jini, kuma suna da ƙananan sakamako. CoQ10 antioxidant ne wanda aka samo a cikin kowane sel a cikin jikin mutum.
Babban aikin CoQ10 shine sauya kayan abinci zuwa makamashi don haɓakawa da kiyaye sel. Wannan kayan aiki yana fara samar da enzymes da aka yi amfani da su don narke abinci tare da sauran mahimman abubuwan aikin sunadarai. A matsayin maganin antioxidant, yana kuma kare sel daga lalacewa ta hanyar tsattsauran ra'ayi. Bincike ya tabbatar da cewa CoQ10 a zahiri yana rage haɗarin kamuwa da cututtukan zuciya da rage haɓakar lipoproteins mai ƙima (wanda aka fi sani da suna "mummunan" cholesterol).
Abin takaici, bincike ya nuna cewa statins din na iya rage ajiyar kayan CoQ10. Sabili da haka, idan mai haƙuri a halin yanzu yana amfani da wannan nau'in magani, yana da mahimmanci a ɗauki kari na CoQ10 don sauƙaƙa ciwon tsoka, kare hanta daga lalacewa da hana faruwar mummunan sakamako masu illa da magunguna suka haifar.
Wani samfurin rage ƙwayar cholesterol shine jan shinkafa mai yisti, wanda aka kirkira ta hanyar dafa shinkafa tare da nau'ikan yisti na Monascus. Samfurin da aka samu ya ƙunshi abubuwa da yawa waɗanda ke taimakawa sarrafa ƙwayar cuta, ciki har da sterols, isoflavones da monounsaturated fatty acids. Monacolin K, wanda yake ɗayan wannan cirewar, abu ne mai sinadarai na halitta wanda ke da tsari mai kama da magunguna Lovastatin da Mevinolin.
Nazarin ya nuna cewa ƙara fitar da yisti na shinkafa mai lalacewa a cikin raguwar 33% na lipoproteins mai ƙarancin yawa, kazalika da yuwuwar karuwar ƙwayar abinci mai ɗimbin yawa ko "mai kyau" cholesterol.
Niacin da omega-3 mai mai
Tun cikin shekarun 1950s, niacin ko bitamin B3 an wajabta shi a matsayin wakili mai tasiri don rage ƙwayar cholesterol da triglycerides. Koyaya, yana da matsala guda ɗaya: dangane da ƙimar, niacin zai iya haifar da redness da itching.
Koyaya, akwai ingantaccen madadin Inositol hexanacinate wani yanki ne wanda bashi da lokaci-lokaci na kwayar niacin shida wanda ke samar da fa'idar wannan mahimmancin bitamin B ba tare da wani rikitarwa ga hanta ba.
Enositol hexanacinate an tabbatar da inganci, musamman wajen magance yawan kitse na mara yawa a cikin jini. Wannan yanayin ana kiranta hyperlipidemia kuma babban haɗari ne ga atherosclerosis da cututtukan zuciya.
Ragewar cholesterol kyauta ba tare da yin amfani da niacin ko bitamin B-3 ba. Wannan zaɓi ne mai kyau ga mutanen da ba su amsa da kyau ga wasu magunguna ba, saboda tasirin sakamako masu sauƙi da ƙanana.
Mutanen da suke shan wannan magani na iya samun masu zuwa:
- jan fuska;
- ciwon kai
- ƙarancin ciki
- karuwar gumi;
- Dizziness
- tashin zuciya
Lokacin da ake buƙatar karin rigakafi don kula da ƙwayar cholesterol, ana ba da tsarin aji da ake kira fibrate.
A cikin shekaru 200 da suka gabata, rabon omega-6 zuwa omega-3 mai mai a cikin abincin ɗan adam ya inganta sosai. Waɗannan abubuwa suna taimakawa sosai don yaƙi da babban tasirin cholesterol, kuma sunada ikon daidaita sashi tsakanin ƙarancin abinci mai ƙarfi.
Mutum yana buƙatar daidaita ma'aunin omega-3 da omega-6 mai kitse a cikin abincinsu don zama lafiya. Abin takaici, menu na yau da kullun suna samar da Omega-6 sosai sosai kuma ba isasshen ƙwayoyin omega-3 mai yawa.
Masana sun yi nuni da cewa, kaso daya-gefen sune babban dalilin cutar zuciya.
Cholesterol sha inhibitors da kuma masu bin umarnin
Idan statins ba zaɓi ne mai kyau ba, ko kuma idan mai haƙuri ya sha wahala sakamakon tasirin, likitan na iya tsara wani magani don kula da ƙwayar cutar cholesterol. Wani madadin gama gari shine inhibitor shan ƙwayoyin cuta.
Wadannan kwayoyi basa barin karamin hanji ya kwashe kwayar cholesterol yadda yakamata. Idan har ba za a iya shan shi ba, to cholesterol din bai kai karfin jini ba. Magungunan kawai da ke akwai a kasuwar shine Ezetimibe. Za'a iya haxa wannan magani tare da statins don sakamako mai sauri. Koyaya, yawancin likitoci suna ba da izinin Ezetimibe kawai kuma sun haɗa shi da abinci mai ƙarancin kitse don taimakawa rage ƙwayar cholesterol.
Wata hanyar da za a rage cholesterol ba tare da mutum-mutumi ba ita ce amfani da dillalan bile acid ko kuma jeri. Wadannan kwayoyi suna aiki ne ta hanyar daure su bile a cikin hanji, toshe kodin cholesterol. Tasirin waɗannan kuɗin ba su yi kama da na sauran ƙwayoyi ba, saboda haka mutane da ke da matakan cholesterol, ana ƙara su kaɗan. Wadannan magunguna suna iya haifar da rashi na bitamin tare da amfani da tsawan lokaci. Rashin bitamin K yana da haɗari musamman saboda bitamin da ke da alhakin tsarin hemostatic.
Masu bin Bile acid sune abubuwan haɗin polymeric waɗanda ke musanya anions, kamar ion loride, don acid ɗin bile. Don haka, suna ɗaukar acid bile. Daga nan hanta tana samar da ƙarin ƙwayoyin bile don maye gurbin waɗanda batattu. Tunda jikin yana amfani da cholesterol don samar da bile acid, yana rage adadin karancin sinadarin lipoprotein da yake yawo a cikin jini. Masu bin Bile acid babban tsari ne na polymer, kuma basu da amfani sosai daga hanjin cikin jini.
Don haka, wadannan kwayoyi tare da bile acid masu alaƙa da miyagun ƙwayoyi an keɓance su ta hanyar hanji.
Abubuwan cholesterol na yau da kullun suna aiki
Hakanan magunguna na zahiri an nuna suna da wasu tasirin cholesterol.
Koyaya, amfanin su yakamata ya kasance tare da sauyi a salon rayuwa.
Ya kamata a cinye ƙananan ƙwayoyin cholesterol. Yana da kyau a kula da motsa jiki.
Haɗe tare da waɗannan, waɗannan tsire-tsire ma suna da tasirin gaske:
- Tafarnuwa.
- Oat bran.
- Artichoke.
- Sha'ir
- Blond psyllium.
Idan kana son rage cholesterol dinka, asirin shine kawai ka canza abincinka na safe. Hada hatsi a cikin karin kumallo na iya rage matakin lipoproteins mai yawa da kashi 5.3% a cikin makonni 6 kawai. Ana bayar da wannan tasirin ne ta hanyar beta-glucan - wani abu ne da ke cikin oats wanda yake ɗaukar cholesterol, don haka hana bayyanar magunan cholesterol. Kwayoyi suna da kyau a ragewan cholesterol, amma saboda yawan adadin kuzarin su, manufarsu ta iyakance.
Tare da yardar likita, ana iya ƙara sa su cikin abincin. Yana da mahimmanci a lura cewa idan akwai magunguna a cikin rubutattun likitan likitancin, shan magunguna na dabi'a don rage cholesterol ba shine dalilin dakatar da magani ba.
Mafi kyawun zaɓi na magani ya dogara da dalilai da yawa. Kafin likita ya rubuta takardar sayan magani don wani magani, ƙwararrun likitan zai gano tarihin gidan mai haƙuri, haɗarin cutar zuciya da wannan cutar, sannan kuma bincika yanayin haƙuri. Yawancin likitoci sun fi son fara magani tare da canje-canje a cikin abinci da motsa jiki. Idan bayan wannan babu sakamako, likitan ya ba da umarnin gyara likita. Ba shi yiwuwa a canza sashi ko nau'in magungunan ba tare da shawarar likita ba, tunda wannan ya kasance tare da ko dai rashin tasirin magani, ko kuma, mafi muni, ci gaban sakamako.
Hakanan, kin amincewa da kwayoyi na taimakawa da tsadar su. Duk da gaskiyar cewa waɗannan kwayoyin suna sha a kullun kuma ba tare da tsangwama ba, statins sun zama nauyi ba kawai ga hanta ba, har ma da walat. Binciken na ainihi na wannan rukuni na kwayoyi ba koyaushe ba tare da maganganu mara kyau, saboda tasirin magungunan na iya zama ƙasa da lura fiye da sakamako masu illa.
Ana ba da bayani game da gumaka a cikin bidiyon a cikin wannan labarin.