Diapiride magani ne tare da tasirin hypoglycemic na tsawon lokaci. A miyagun ƙwayoyi nasa ne da dama sulfonylurea Kalam.
Sunan kasa da kasa mai zaman kansa
INN kudade - Glimepiride.
Diapiride magani ne tare da tasirin hypoglycemic na tsawon lokaci.
ATX
Lambar ATX: A10VB12.
Saki siffofin da abun da ke ciki
Ana yin magungunan a cikin nau'ikan allunan tare da matakan daban-daban na abu mai aiki. A cikin kunshin kwali shine allunan 30 a cikin blisters. 1 kwamfutar hannu 1 ya ƙunshi 2, 3 ko 4 na glimepiride (abu mai aiki). Allunan tare da sashi na 2 MG sune hasken kore, 3 MG mai launin rawaya, 4 MG haske ne mai shuɗi.
Abubuwan da ke tattare da Allunan sun hada da irin waɗannan magabata:
- lactose monohydrate;
- microcrystalline cellulose;
- sodium sitaci glycolate;
- povidone;
- baƙin ƙarfe baƙin ƙarfe;
- magnesium stearate;
- indigo carmine.
Glimepiride yana da tasirin hypoglycemic ta hanyar ƙarfafa sakin insulin.
Aikin magunguna
Glimepiride yana da tasirin hypoglycemic ta hanyar ƙarfafa sakin insulin. Abubuwan suna aiki akan membranes na β-sel na pancreas, rufe tashoshin potassium. Sakamakon haka, wadannan sel suna mai da hankali ga matakan sukari a jiki, kuma ana fitar da insulin cikin sauki da sauri.
Hakanan akwai haɓakar ƙwaƙwalwar ƙwayoyin sel zuwa insulin, kuma amfani da hanta ya ragu. A lokaci guda, ana hana gluconeogenesis. Lipid da ƙwayar tsoka suna kama kwayoyin glucose da sauri saboda ƙaruwa a cikin adadin sunadarai na safarar abubuwa.
Abubuwan da ke aiki suna rage ƙarfin damuwa na rashin ƙarfi ta hanyar ƙarfafa ƙwayar ting-tocopherol da haɓaka aikin aikin enzymes na antioxidant.
Pharmacokinetics
Bayan gudanar da baki, glimepiride yana saurin narkewa a cikin narkewa kuma ya shiga cikin jini. Cin abinci baya rage shaye-shayen maganin. Wannan abun ya kai matsayin mafi girman hankali a cikin jini na jini a cikin awanni 2-2.5.
Bayan gudanar da baki, glimepiride yana saurin narkewa a cikin narkewa kuma ya shiga cikin jini.
Glimepiride yana nunawa ta hanyar ɗaure mai kyau ga furotin na jini (99%). Ana aiwatar da metabolism na miyagun ƙwayoyi a cikin hanta. Abubuwan da ke haifar da metabolites sune kodan da hanjinsu ke kwance. An cire kwayar cutar daga jiki a cikin awanni 10-16. Yayin shan Diapiride, ba'a lura da tarin abubuwa a cikin jikin mutum ba (har ma da tsawan amfani).
Alamu don amfani
Ana amfani da maganin don magance marasa lafiya da nau'in ciwon sukari na II II. An tsara allunan lokacin da ba shi yiwuwa a daidaita sukari na jini ta amfani da abinci mai kyau da kuma motsa jiki.
Contraindications
Haramun ne a sha magani idan akwai wadannan abubuwan da ke faruwa:
- Musu rashin haƙuri ga sulfonamides.
- Rashin hankali ga abubuwan da aka gyara.
- Coma
- Ketoacidosis.
- Mummunan siffofin hanta ko koda cuta.
- Type 1 ciwon sukari.
- Lokacin daukar ciki da lactation.
- Shekarun yara.
Tare da kulawa
A karkashin tsananin kulawa na likita, ana amfani da maganin don gudanar da ayyukan gaggawa, giya, zazzabi, rashin aikin thyroid, karancin adrenal da cututtuka masu tsauri.
Bayan tsoma bakin tiyata mai tsanani, raunin da ya faru, ƙonewa, an shawarci marasa lafiya da su canza zuwa maganin insulin.
Yadda za a ɗauki diapiride?
Ana ɗaukar maganin a baka tare da ruwa kaɗan. Yana da kyau a hada shan allunan tare da abinci don rigakafin cututtukan cututtukan zuciya.
Tare da ciwon sukari
Don lura da cututtukan da ba na insulin-dogara da II na ciwon sukari mellitus ba, ana shan wannan magani sau 1-2 a rana. A farkon kashi, kashi shine 1 MG cikin sharuddan glimepiride. Idan ya isa ya daidaita yadda ake sarrafa glucose a cikin jini, to ba a kara kashin ba.
Tare da rashin isasshen sakamako, ana ƙara yawan kashi zuwa 2, 3 ko 4 MG. A tazara tsakanin canje-canje sashi ya zama akalla kwanaki 7. Wasu lokuta ana tsara marasa lafiya 6 MG na glimepiride kowace rana (matsakaicin mafi yawan maganin yau da kullun).
Likitoci na iya ba da izinin sarrafa maganin tare da metformin ko insulin don cimma sakamako mafi girma. Shan waɗannan magunguna na iya haifar da ƙaruwa mai ɗorewa a cikin ƙarfin insulin. A wannan yanayin, an rage kashi ko an soke gaba ɗaya.
Side effects na Diapyrid
A wani bangare na bangaren hangen nesa
Yayin magani, rikicewar gani na wucin gadi (rikicewar wucin gadi) na iya faruwa. Sanadin wannan sakamako na gefe shine canji a cikin sukarin jini.
Don lura da cututtukan da ba na insulin-dogara da II na ciwon sukari mellitus ba, ana shan wannan magani sau 1-2 a rana.
Gastrointestinal fili
Tasiri kan narkewa:
- tashin zuciya da amai
- zawo
- ciwon ciki;
- cututtukan hanta (hepatitis, hanta, da dai sauransu).
Hematopoietic gabobin
Sakamakon sakamako daga tsarin basur:
- thrombocytopenia;
- leukopenia;
- anemia
- granulocytopenia;
- erythrocytopenia;
- agranulocytosis;
- kwankwantin.
Tsarin juyayi na tsakiya
Daga gefen tsarin juyayi na tsakiya ana lura:
- ciwon kai
- Dizziness
- rikicewar hankali;
- rashin bacci
- gajiya;
- jihohi masu raha;
- raguwa a cikin halayen psychomotor;
- rashi magana;
- rawar jiki;
- katsewa.
Daga gefen metabolism
Negativearancin tasiri akan metabolism an bayyana shi ta hanyar hypoglycemia.
Cutar Al'aura
Yayin gudanarwa, halayen rashin lafiyan suna iya yiwuwa:
- fata mai ƙyalli;
- urticaria;
- kurji
- rashin lafiyan vasculitis.
Don tsawon lokacin magani tare da miyagun ƙwayoyi daga tsarin juyayi na tsakiya, ciwon kai na iya bayyana.
Don tsawon lokacin magani tare da miyagun ƙwayoyi daga tsarin juyayi na tsakiya, ƙaiƙayi na iya bayyana.
Don tsawon lokacin magani tare da miyagun ƙwayoyi daga gefen tsarin juyayi na tsakiya, rikice-rikice na iya bayyana.
Don tsawon lokacin magani tare da miyagun ƙwayoyi daga tsarin juyayi na tsakiya, rashin bacci na iya bayyana.
Don tsawon lokacin magani tare da miyagun ƙwayoyi daga tsarin juyayi na tsakiya, ƙara yawan gajiya na iya bayyana.
A lokacin jiyya tare da miyagun ƙwayoyi daga tsarin juyayi na tsakiya, yanayin damuwa na iya bayyana.
Tsawon lokacin magani tare da miyagun ƙwayoyi daga tsarin juyayi na tsakiya, raɗaɗi na iya bayyana.
Tasiri kan ikon sarrafa abubuwan inji
A miyagun ƙwayoyi na iya rage saurin halayen psychomotor kuma yana haifar da tsananin fushi. A farkon jiyya, har da lokacin daidaita allurai, ba a ba da shawarar fitar da motoci da yin wasu ayyukan da ke buƙatar haɓakar mai da hankali ba.
Umarni na musamman
Idan matakin glucose a cikin jini ya ragu daga mafi ƙarancin adadin yau da kullun (1 mg na glimepiride), ana bada shawara a hankali dakatar da amfani da maganin. Ana iya samun sakamako na hypoglycemic a wannan yanayin ta amfani da abincin warkewa (ba tare da amfani da magunguna ba).
Yayin aikin jiyya, kuna buƙatar saka idanu glucose jini, gemocosylated haemoglobin, da hanta, farin jini da faranti a cikin jini.
Yi amfani da tsufa
An yarda da amfani da kayan aikin don marasa lafiya na nau'ikan shekaru daban-daban, ban da yara. Amma tsofaffi tare da yin amfani da kwayoyin hana daukar ciki na iya tsawan lokaci. Don guje wa wannan ilimin, likitoci suna ba da haƙuri ga tsofaffi abinci na musamman da ƙarancin magunguna (in ya yiwu).
Aiki yara
An yarda da amfani da maganin bayan shekaru 18.
Yi amfani da lokacin daukar ciki da lactation
A lokacin daukar ciki da lactation, shan wannan magani yana contraindicated.
Idan matakin glucose a cikin jini ya ragu daga mafi ƙarancin abinci na yau da kullun (1 mg na glimepiride), ana ba da shawarar a daina amfani da maganin.
Aikace-aikacen aiki mara kyau
A cikin cututtukan koda masu raɗaɗi, babu wani magani da aka tsara. Irin waɗannan marasa lafiya ana tura su zuwa insulin therapy. A matakin farko na gazawar koda, yin amfani da allunan zai yiwu a ƙarƙashin tsananin kulawa daga likita.
Amfani don aikin hanta mai rauni
Kwayar cuta mai saurin hanta cuta ce ta amfani da miyagun ƙwayoyi. A cikin cututtukan cututtuka masu sauƙin matsakaici ko matsakaici, gudanarwarsa cikin ƙananan allurai mai yiwuwa ne. Yakamata tare da kula da hanta.
Yawan abin da ya faru na Diapiride
Doaryewar ƙwayar ƙwayar cuta yana haifar da bayyanar halayen hypoglycemic (raguwa mai yawa a cikin sukari na jini). A wannan yanayin, mai haƙuri yana jin gajiya, nutsuwa, farin ciki. Yiwuwar asarar ilimi. Don kawar da alamun cutar yawan ƙwayar cuta, suna yin magani.
Doaryewar ƙwayar ƙwayar cuta yana haifar da bayyanar halayen hypoglycemic (raguwa mai yawa cikin sukari jini).
Yin hulɗa tare da wasu kwayoyi
Ya kamata a sha miyagun ƙwayoyi tare da taka tsantsan tare da irin waɗannan magunguna kamar:
- Fluconazole
- Fankamara
- Azapropazone.
- Sulfinpyrazone.
- Oxyphenbutazone.
- Pentoxifylline.
- Tritokvalin.
- Abubuwan cikin rashin kunya.
- Fenfluramine.
- Probenecid.
- Anticoagulants daga coumarin rukuni.
- Salicylates.
- Wasu magungunan rigakafin cutar (MAO inhibitors).
- Fibrates.
- Fluoxetine.
- Harshen Cyclophosphamide.
- Feniramidol.
- Ifosfamide.
- Miconazole
- Tetracycline da rigakafin ƙwayoyin cuta na quinolone.
- Sauran magungunan cututtukan jini.
- Maganin steroid din anabolic.
- ACE masu hanawa.
- PASK (para-aminosalicylic acid).
Ana lura da rage tasirin magungunan idan aka hada su tare da Phenothiazine da ire-irensa.
Tare da yin amfani da waɗannan kuɗin lokaci ɗaya, ana inganta tasirin hypoglycemic na Diapiride. Ana lura da rage tasirin magungunan lokacin da aka haɗu tare da Phenothiazine da abubuwan da ya samo asali, estrogens da progestogens, glucagon, nicotinic acid, corticosteroids, barbiturates, Phenytoin, Acetazolamide, diuretics da magunguna don maganin cututtukan thyroid.
Amfani da barasa
Magungunan suna da karfin jituwa tare da ethanol. Giya na iya kasancewa da haɓaka da rage tasirin cutar Diapiride.
Analogs
Akwai irin waɗannan analogues na miyagun ƙwayoyi:
- Gliclazide.
- Maninil.
- Mai ciwon sukari.
- Glidiab.
- Glurenorm.
Magunguna kan bar sharuɗan
Zan iya saya ba tare da takardar sayan magani ba?
Ana bayar da maganin ta hanyar sayan magani.
Farashi
Kudin Diapiride a cikin kantin magunguna sun kama daga 110 zuwa 270 rubles, gwargwadon sashi na abu mai aiki.
Yanayin ajiya na miyagun ƙwayoyi
Riƙe allunan a cikin busassun duhu da duhu daga isar yara, a yanayin zafi har zuwa + 25 ° C.
Ranar karewa
Rayuwar shelf shine shekaru 2.
Mai masana'anta
Kamfanin masana'antar PJSC "Farmak" (Ukraine).
Nasiha
Lyudmila, dan shekara 44, Izhevsk.
Na fara amfani da wannan magani kamar yadda likita ya umarta don rage sukarin jini. Magungunan suna da araha kuma suna da tasiri sosai. Yana taimakawa wajen kiyaye matakan sukari.
Alexey, 56 years old, Moscow.
Na kasance ina fama da ciwon sukari na 2 fiye da shekaru 5. Ina shan waɗannan kwayoyin a cikin ƙaramin sashi. Tare da amfani na yau da kullun, matakin glucose na jini ya zama barga. Abubuwan da basuda sakamako ba faruwa. Amma na yi kokarin hada magunguna da abinci don kaucewa faduwar sukari.
Anna, 39 years, Voronezh.
Masanin ilimin endocrinologist ya ba da shawarar shan wannan maganin na antidiabetic. Na yi haƙuri da maganin a sauƙaƙe, Ba na jin wani sakamako masu illa. Farashinta ya dace da ni sosai. Gwanin jini yana cikin iyaka gwargwado. Ina bayar da shawarar shi!
