A miyagun ƙwayoyi Novonorm - umarnin da sake dubawa ga masu ciwon sukari

NovoNorm shine mai kara kuzari. A cikin ciwon sukari na mellitus, ana amfani da wannan magani lokacin insulin bai isa cikin jinin mai haƙuri ba, dole ne a ƙarfafa karfinta. Wani fasali na maganin shine tasirin sa mai sauri da kuma gajere, wanda zai baka damar amfani da shi dan daidaita matakin postprandial glycemia, watau rage glucose daga abinci.

Idan an yi amfani dashi ba daidai ba, NovoNorm na iya haifar da hypoglycemia, don haka yana da matukar muhimmanci a zaɓi isasshen sashi. Ana amfani da magani na farko da likita, ya kuma rubuta takardar sayan magani, gwargwadon abin da zaku iya siye magungunan. A nan gaba, mai ciwon sukari na iya daidaita sashi, da amfani da shawarwarin daga umarnin don amfani.

Abun ciki da nau'i na saki

NovoNorm an ƙaddamar da shi ta hanyar damuwa NovoNordisk, sanannen masanin masana'antar Danish na magunguna da samfurori masu alaƙa ga masu ciwon sukari. Allunan an yi su ne a Jamus da Denmark. Aiki mai amfani da maganin, repaglinide, asali ne na amino acid kuma yana cikin bayanan sirrin gajere. Ya fito daga asalin Jamusawa (mai samar da Beringer Ingelheim).

Ciwon sukari da hauhawar jini zai zama abin da ya wuce

• Normalization na sukari -95%
• Cirewa kan jijiyoyin mara wuya - 70%
• Cire zuciyar mai karfin zuciya -90%
• Rabu da cutar hawan jini - 92%
• Increasearuwar kuzarin rana, inganta bacci da dare -97%

Tabletaya daga cikin kwamfutar hannu NovoNorm na iya ƙunsar 0.5, 1 ko 2 mg na abu mai aiki. Bayan wannan, an haɗa sitaci, povidone, potassium polyacrylate, pluronic, glycerin, alli hydrogen phosphate, da dyes. Abubuwan tallafi ne na taimako, wato, basu da tasirin warkewa.

Yadda za'a tantance asalin magani:

1. Don kare kai daga fakes, kowace alamar kwamfutar hannu alama ce tare da alamar NovoNordisk - bijimin tsafta na Masar na d ancient a.
2. An sanya miyagun ƙwayoyi a cikin blister foil, kowane ɗayan yana da Allunan 15.
3. An bayarda da adon fuska tare da juzu'i, wanda zai baka damar raba kashi na yau da kullun ba tare da amfani da almakashi ba.
4. Launi na allunan kwayoyi daban-daban sun bambanta: 0,5 mg fari, 1 mg rawaya, 2 mg ruwan hoda.

Farashin kayan haɗi wanda ya ƙunshi Allunan 30 bai wuce 230 rubles ba. Ana iya adana miyagun ƙwayoyi na shekaru 5 a zazzabi na 15-30 ° C.

Ka'idar aiki ta NovoNorma

Repaglinide wani bangare ne na rukunin magunguna da ake kira meglitinides. Kuna iya gane su a ƙarshen glinid da sunan. Abubuwan sunadarai ne na amino acid iri daban-daban, musammam ma maganin gargajiya - carbamoyl-methyl-benzoic. Abun ya sami damar ɗaure wa wani yanki na musamman na tashoshin potassium da ke kan membrane na ƙwayoyin beta na pancreatic. A ƙarƙashin tasirin maganin repaglinide, ana katange waɗannan tashoshi, wanda ke haifar da shigowar alli a cikin sel da kuma ƙara haɓakar insulin.

Sakin insulin da NovoNorm ya fara ne mintina 10 bayan kwamfutar hannu ta shiga cikin narkewar abinci. Ana gano matsakaicin matakin jini a cikin minti 50. Idan kun sha miyagun ƙwayoyi na mintina 15 kafin cin abinci, haɓakar glucose na jini da haɓakar insulin zai daidaita cikin lokaci, wanda ke nufin cewa glucose na iya barin tasoshin cikin sauri da kuma cikakke.

Ba kamar shahararren abubuwan da ake amfani da su ba (Maninil, Amaril, Glibenclamide, da sauransu), aikin NovoNorm ya dogara ne da glycemia. Tare da sukari na yau da kullun, sau da yawa ba shi da aiki fiye da yawan sukari. Bayan aiwatar da Repaglinide, matakan insulin sun koma al'ada bayan sa'o'i 3. A cewar likitocin, wannan fasalin yana rage tasirin girma da kuma tsananin karfin jiki idan ya kasance yawan zubar jini. Irin wannan gajeriyar haɓakar sakin insulin ana ɗaukarsa yadu, yana hana hanzarin rage ƙwayoyin beta, ya kuma inganta ciwan sukari.

Siffofin kawarwa daga jiki

Repaglinide zai iya samun nutsuwa cikin hanzari a cikin narkewa, wanda saboda farkon farkon aikin sa. Bioavailability da kuma taro na ƙarshe na abu a cikin jini ya bambanta sosai (har zuwa 60%) a cikin masu ciwon sukari daban-daban, sabili da haka, dole ne a zaɓi sashi don kowane mai haƙuri daban-daban.

Abubuwan da hanta ke kawowa shine sake daukar hanta, bayan sa'a daya an rage maida hankali da rabi. Babban fasalin masana'antar magunguna na wani abu shine tsallake daga jikin mutum galibi ta hanyar narkewar abinci. Dangane da umarnin, 92% na repaglinide suna fitowa tare da feces, 2% daga cikinsu a cikin nau'i na abu mai aiki, ragowar 90% a cikin hanyar metabolites. Kodan sun kusan kimanin 8%, wanda ke ba da damar amfani da NovoNorm a cikin masu ciwon sukari tare da mummunan cututtukan koda. Bayan sa'o'i 5, ba a sake gano musibar cikin jini ba.

Wanene aka wajabta maganin?

An wajabta NovoNorm don masu ciwon sukari na 2 a cikin waɗannan lambobin:

1. Tare tare da metformin nan da nan bayan bayyanar cutar, idan glycated haemoglobin ya fi 9%, wanda ke nuna rashin tabbas na ciwon sukari mellitus ko kuma ci gaba da sauri.
2. A matsayin mai sauyawa na maganin ƙwayoyin cuta (sulfonylureas), idan suna contraindicated saboda cutar koda, halayen ƙwayar cuta.
3. A matsayin ɓangare na jiyya mai rikitarwa, marasa lafiya da ke da ciwon sukari na dogon lokaci, idan suna da rashi na insulin ko kuma lokaci na 1 na samarwarsa ya rikice (sukari ya tashi da sauri kuma baya fada na dogon lokaci bayan cin abinci).
4. Masu fama da cutar sankara wadanda basa iya tsara abincinsu. Ana iya canza kashi na NovoNorm dangane da adadin carbohydrates a abinci.

Koyarwar don amfani yana ba da shawarar shan NovoNorm tare da metformin da glitazones. Dangane da sake dubawa, miyagun ƙwayoyi suna tafiya da kyau tare da dukkanin rukuni na jamiái na hypoglycemic, ciki har da insulin. Iyakar abin da banda shi ne shirye-shiryen sulfonylurea. Haɗin su tare da NovoNorm abu ne mai karɓa, amma ba da shawarar ba, tunda yana iya haifar da matsanancin rashin ƙarfi kuma yana cutar da yanayin ƙwayoyin beta.

Contraindications

Jerin maganin contraindications don yin amfani da NovoNorm a cikin ciwon sukari mellitus:

Zaɓin sashi

NovoNorm yana shan mintina 15 kafin cin abinci na carbohydrate. Umarni ya ba da shawarar rarraba shi a allurai sau 2 a rana daidai gwargwado.

Sashi zaɓi ne da za'ayi tare da m saka idanu na glycemia. Dokokin Zabi:

1. Maganin farawa shine 0.5 MG.
2. Idan ba'a biya diyya ga ciwon sukari ba, ana ƙaruwa ne bayan mako 1 zuwa 1 MG.
3. Ta hanyar haɓaka ɗaukar nasara ta hanyar 0.5 mg, ana iya kawo har zuwa 4 MG a cikin kashi 1. Matsakaicin adadin yau da kullun shine 16 MG. Idan ba ta ba da ikon sarrafa ciwon sukari ba, mai haƙuri yana buƙatar daidaita abincin, kuma idan wannan ma'aunin ba shi da tasiri, canza zuwa magunguna masu ƙarfi ko insulin.

Matakan da ba a so

Dangane da sake dubawa game da masu ciwon sukari da ke shan miyagun ƙwayoyi, galibi suna haɗuwa da raguwar da ba a so a cikin sukari bayan shan kwaya. Dalilinsa na iya zama mai wuce gona da iri na maganin repaglinide, karancin carbohydrates a abinci, narkewar mutum, damuwa na jiki da na hankali. Hadarin yana da yawaitar haɗarin cutar hypoglycemia ta umarnin akai-akai (1-10%). Tare da yiwuwar guda ɗaya mai yiwuwa ne - zawo da ciwo a cikin yankin na ciki.

Sauran tasirin sakamako masu ƙarancin tasiri ba su da yawa, a cikin ƙasa da 0.1% na marasa lafiya. NovoNorm na iya haifar da rashin lafiyan jiki, maƙarƙashiya, tashin zuciya, ba da gudummawa ga haɓakar haɓakar enzymes na hanta.

Analogs da maye gurbin NovoNorma

Me zai iya maye gurbin NovoNorm idan ba shi da haƙuri ko ba ya cikin magunguna:

A cikin ciwon sukari na mellitus, maye gurbin NovoNorm tare da cikakken analogues ana iya yin shi daban-daban, suna shan sabon magani a cikin kashi ɗaya. Canzawa zuwa kowane kwamfutar hannu daga teburin da ke sama yana buƙatar zaɓin kashi kuma ana iya yin shi kawai a ƙarƙashin kulawa da saiti na likita.

Ra'ayoyi game da miyagun ƙwayoyi