Isofan insulin aikin injiniyan ɗan adam

Magungunan yana cikin insulins na matsakaici. A zahiri, wannan shine insulin na mutum, wanda aka samo shi da godiya ga fasahar DNA.

Aikin magunguna

Insulin isulin yana da tasirin jini. Yana hulɗa tare da masu karɓa na musamman akan membrane sel na cytoplasmic kuma yana samar da tsarin insulin-receptor wanda ke motsa ayyukan cikin ciki, wanda ya haɗa da haɗin tushen babban enzymes (pyruvate kinase, hexokinase, glycogen synthetase).

Increasearin hauhawar cikin jijiyoyin jini yana haifar da raguwa a matakin sa cikin jini. Hakanan yana ba da gudummawa ga rage yawan samar da glucose ta hanta, haɓaka sha da sha ta nama. Stimulates glycogenogenesis, lipogenesis, abubuwan gina jiki.

Yawan sha, saboda abin da magungunan ke da tasiri na dindindin, ya dogara da dalilai da yawa lokaci guda: wurin da hanyar gudanarwa, kashi. A wannan batun, aikin insulin zai iya canzawa zuwa babban adadin. Haka kuma, ana iya lura da ire-iren wadannan halayen ba wai kawai a cikin mutane daban-daban ba, har ma a cikin haƙuri ɗaya.

Bayan allurar subcutaneous, a matsakaita, ƙwayar ta fara aiki bayan sa'o'i 1.5, kuma mafi girman tasirin yana faruwa a tsakanin tazara tsakanin 4 zuwa 12. Tasirin maganin yana tsawan awanni 24.

Farkon tasirin sakamako da kuma cikakkiyar ɗaukar ƙwayar insulin ya bambanta:

• daga wurin allura (ciki, gindi, cinya);
• a kan maida hankali kan kwayar cutar a cikin magani;
• a kan adadin insulin da aka sarrafa (kashi).

Sauran abubuwan:

1. Babu a cikin nono.
2. Ba a rarraba ba akan kyallen takarda.
3. Ba ya karyewa ta hanyar tsakiyar mashigin mahaifa.
4. 30-80% da kodan ya fitar.
5. An lalata shi ta hanyar insulinase galibi a cikin kodan da hanta.

Yaushe lokacin shan insulin isofan

• Ciwon sukari irin na I da II.
• Matakan jure magungunan baka na tsotsar jini.
• A lokacin hada magani, m jure magunguna na wannan rukuni.
• Nau'in cutar siga ta II a cikin mata masu juna biyu.
• Cututtukan ciki.

Contraindications

Hypoglycemia, rashin lafiyar jiki, kazalika da hypoglycemia yayin daukar ciki.

Sakamakon sakamako na insulin kwayoyi suna isofan

Mai dangantaka da tasirin metabolism:

Hypoglycemia:

1. haɓaka giyar rabuwa
2. yunwa
3. pallor na fata
4. girgiza, tachycardia,
5. farin ciki
6. ciwon kai
7. paresthesia a cikin bakin;
8. matsanancin rashin ƙarfi, wanda aka haɓaka tare da haɓakar ƙwaƙwalwar ƙwayar cuta.

Bayyananniyar bayyanar cututtuka masu wuya ce:

• Rubutun 'Quincke's edema,
• fata fitsari
• amafflactic rawar jiki.

Sauran:

• yawanci a farkon jiyya na jigilar rashi ne;
• kumburi.

Ayyukan gida

1. kumburi da itching a cikin allura;
2. hyperemia;
3. lipodystrophy a cikin allura (tare da tsawan lokacin amfani).

Haɗa kai

Inganta tasirin insulin na hypoglycemic:

• MAO masu hanawa;
• magungunan baka na haila.
• bromocriptine;
• carbonic anhydrase inhibitors;
• sulfonamides;
• fenfluramine;
• shirye-shirye dauke da ethanol;
• ACE masu hanawa;
• marasa zaɓi na beta-blockers;
• mebendazole;
• shirye-shiryen lithium;
• hanyoyin tetracyclines;
• ketoconazole;
• magungunan anabolic steroids;
• cyclophosphamide;
• octreotide;
• pyridoxine;
• Clofibrate;
• akarijin.

Lallai ne yanayin rashin lafiyar insulin:

1. thiazide diuretics;
2. maganin hana haihuwa;
3. diazoxide;
4. kwayoyin hodar iblis;
5. morphine;
6. glucocorticoids;
7. danazole;
8. heparin;
9. BKK;
10. tricyclic antidepressants;
11. nicotine;
12. m
13. clonidine;
14. phenytoin.

Amma salicylates da reserpine zasu iya raunanawa da haɓaka aikin insulin.

Yawan damuwa

Idan akwai yawan abin sama da ya kamata, yawan jini zai iya faruwa.

Tsarin cututtukan hypoglycemia

Marasa lafiya na iya jure yanayin rashin ƙarfi ta hanyar cin wani sukari, alewa ko abinci mai cike da ƙwayoyi. Sabili da haka, marasa lafiya da ciwon sukari ya kamata koyaushe suna da sukari, kukis, Sweets ko ruwan 'ya'yan itace tare da su.

A cikin yanayin hypoglycemia mai tsanani, lokacin da mai haƙuri ya rasa hankali, 40% na dextrose ko glucagon ana allurar cikin ciki.

Ana iya sarrafa insulin na ƙarshe na halittar jiki duka biyu intramuscularly da kuma subcutaneously. Lokacin da hankali ya sake komawa ga mutum, yana buƙatar cin abinci mai arzikin carbohydrate, wannan zai hana sake haɓakar ƙwanƙwasawa.

Sashi da gudanarwa

Yawan kwatancen sc ana ƙaddara ta ƙwararrun masani daban a cikin kowane yanayi. Ya dogara ne da matakin glucose a cikin jinin mai haƙuri. Matsakaicin yawan maganin yau da kullum ya bambanta daga 0,5 zuwa 1 IU / kg, ya dogara da matsayin matakin glucose a cikin jini da kuma kan halaye na mutum na mai haƙuri, yadda yake bi da ɗan adam da ƙwararrun injin kansa na insulin isofan.

Isofan insulin, azaman magani ne na ɗan adam da asalin halitta, yawanci ana allurar dashi a cikin cinya, amma za'a iya sanya allura cikin buttock, bangon ciki na ciki, da ƙyallen ƙashin gwiwa. Zazzabi na miyagun ƙwayoyi da aka sarrafa ya kamata ya zama zazzabi dakin

Kariya da aminci

A cikin yankin ilimin jikin, yana da shawarar canza sashin allura. Wannan zai hana haɓakar lipodystrophy. Tare da ilimin insulin, kuna buƙatar kulawa da sukari jini koyaushe.

Baya ga gaskiyar cewa insulin ɗan adam da keɓaɓɓen injiniya na iya wucewa, abubuwan da ke haifar da ƙin jini na iya zama:

1. tsallake abinci;
2. zawo, amai;

Cututtukan da ke rage buƙatar ƙwayar hormone-ƙwayar cuta (ƙwayar ƙwayar cuta, pituitary, adrenal cortex, glandar thyroid, rauni na koda da aikin hepatic);

1. maye gurbin magani;
2. canjin yankin allura;
3. haɓaka aiki na jiki;
4. hulɗa tare da wasu kwayoyi.

Idan an sanya insulin na ɗan adam da kwayoyin halitta ba tare da izini ba ko kuma sashi ba daidai bane, hyperglycemia na iya faruwa, alamomin wanda yawanci ke haɓaka a hankali (awanni da yawa ko ma kwanaki). Hyperglycemia yana tare da:

• bayyanar ƙishirwa;
• bushe bakin
• urination akai-akai;
• tashin zuciya, amai;
• asarar ci;
• farin ciki
• bushewa da jan launi na fata;
• warin acetone daga bakin.

Idan magani na lokaci-lokaci don cututtukan hyperglycemia ba zai yiwu ba tare da nau'in ciwon sukari na I, wata cuta mai haɗari mai haɗari ga rayuwa, ketoacidosis, na iya haɓaka.

A cikin cutar Addison, gurguntar ƙwayar thyroid, hanta da aikin koda, hypopituitarism da ciwon sukari mellitus a cikin tsofaffi, ya zama dole don daidaita sashi kuma a hankali sanya magungunan ɗan adam da injin ƙirar asali.

Hakanan ana iya buƙatar canjin kashi a lokuta inda mara lafiya ya canza abincin da ya saba ko ya ƙaru da yawan motsa jiki.

Bil adama da injin ɗan adam ya rage haƙuri da barasa. Dangane da canji a cikin nau'in insulin, ainihin manufarta, akwai babban yiwuwar raguwa a cikin ikon fitar da motoci ko sarrafa hanyoyi daban-daban.

Ba a ba da shawarar darussan don sauran nau'ikan ayyukan haɗari waɗanda ke buƙatar mutum ya zama mai saurin mai hankali da saurin motsi da tunanin mutum.

Kudinsa

Farashi na Isofan a cikin kantin magunguna na Moscow ya tashi daga 500 zuwa 1200 rubles, gwargwadon sashi da mai samarwa.