Barkewar cholesterol a cikin jini yana haifar da ci gaban yanayi mai haɗari. Tare da hyperglycemia, tsarin zuciya da jijiyoyin jini ya tarwatse, atherosclerosis ya bayyana, kuma manyan filayen kitse suna gudana akan jijiyoyi da jijiyoyin jini.
Lokacin da tasoshin jini suka zama cikas, kewayawar jini sai ƙaruwa yake yi da hauhawar jini. Wannan na iya haifar da bugun zuciya, bugun jini, da gudawa. Duk wannan yakan haifar da mutuwa.
Musamman haɗarin haɓakar atherosclerosis sune masu ciwon sukari, a cikin su, wanda, a kan asalin cutar hauka, duk jikin ya rikice. Sabili da haka, suna buƙatar kulawa da lafiyarsu a hankali kuma kada su ƙyale cholesterol masu haɗuwa cikin jini.
A yau, kamfanonin harhada magunguna suna bayar da ton na ƙananan ƙwayoyin cholesterol. Ofayan mafi kyawun kwayoyi shine simvastol. Amma kafin shan magani, ya kamata ku fahimci kanku da umarnin don maganin kuma ku nemi likita.
Tsarin magunguna, abun da ke ciki da nau'i na saki
Simvastol ya toshe ayyukan cholesterol kuma yana hana ayyukan enzyme da ke tattare da kwayar mevalonate. Wannan abu yana rage maida hankali na triglycerides, low li highpropoins mai yawa a cikin jini.
Magungunan yana da sakamako mai tarawa, don haka ana iya ganin tasirin sa kawai bayan kwanaki 14 da amfani. Simvastol yana cikin hanzari a cikin rafi na jini, an sami mafi girman yawan hankali a cikin minti 120 bayan gudanarwarsa.
A cikin hanta, an canza magungunan, wanda ke haifar da samuwar beta-hydroxyl acid, wanda ke da tasirin magunguna masu ƙarfi. Cire rabin rayuwar metabolites shine 2 hours. Suna fita daga jiki da farko ta hanjin hanji.
Babban kayan aikin simvastol shine simvastatin. Ana samun wannan fili ta hanyar fermentation na Aspergillus terreus molds.
Componentsarin abubuwan haɗin maganin:
- macrogol;
- citric acid da lactose monohydrate;
- baƙin ƙarfe;
- butamamarayinan,
- magnesium stearate;
- baƙin ƙarfe;
- titanium dioxide da sauransu.
Akwai magungunan a cikin kwamfutar hannu. Packageaya daga cikin kunshin ya ƙunshi Allunan 14 ko 28. A cikin kwalliyar ruwan hoda akwai 10 mg, a cikin rawaya - 20 MG, a launin ruwan kasa - 40 MG na kayan aiki.
Manuniya da contraindications
Amfani da simvastatin an nuna shi ne don nau'in hypercholesterolemia na farko IIa ko IIb tare da karuwar yiwuwar haɓaka atherosclerosis tare da rashin ingancin maganin abinci da aikin motsa jiki. Hakanan, ƙwayar za ta iya taimakawa tare da ischemia na zuciya a matsayin rigakafin abin da ya faru na bugun zuciya, bugun zuciya.
An wajabta Simvastol don manyan ƙwayar cholesterol, haɗe tare da hauhawar jini. An wajabta magunguna yayin shirye-shiryen farfadowa don rage yiwuwar rikitarwa.
Contraindications don yin amfani da simvastatin - cutar hanta, myopathy, rashin haƙuri ga abubuwan da ke cikin miyagun ƙwayoyi. Ba a ba da magani ba a ƙuruciya da ƙuruciya.
Tare da taka tsantsan, ana amfani da simvastol a cikin waɗannan lambobin:
- cututtukan hanta na kullum;
- barasa;
- tashin hankali na ruwa-electrolyte ma'auni;
- karancin jini;
- raunin da ya faru
- gazawar koda
- atonicity daga cikin tsokoki na kasusuwa;
- rikicewar endocrin;
- mummunan cututtukan cututtuka;
- kasawa a cikin tafiyar matakai na rayuwa;
- ciki da hepatitis B.
Hakanan, bai kamata a ɗauki allunan bayan kowane tsarin tiyata ba. Musamman, maganin yana contraindicated a cikin dasawa na gabobin ciki lokacin da ake amfani da immunosuppressants.
Umarnin don amfani da allunan
Jagorar don amfani da miyagun ƙwayoyi ta ce ya bugu sau ɗaya a rana da maraice, an wanke shi da ruwa. Haka kuma, lokacin shan Simvastol bai kamata a danganta shi da amfani da abinci ba.
Kafin farawa da lokacin jiyya, yakamata a kula da tsarin abinci na anticholesterol. A matakin farko na magani, ana bada shawara a sha Allunan a sashi na 10 da 20 MG.
Ya danganta da tsananin yanayin hypercholesterolemia, likita zai iya canza adadin abu mai aiki daga 10 zuwa 80 MG kowace rana. Idan ya cancanta, kowane kwana 28 likita yana daidaita sashi. A cikin mafi yawan marasa lafiya, ana samun iyakar warkewa ta hanyar shan 20 mg na Simvastol kowace rana.
Tare da hypercholesterolemia na gado (homozygous), adadin maganin yau da kullun shine 40 MG / rana ko 80 MG kowace rana, ya kasu kashi uku (20/20/40 mg).
Tare da cututtukan zuciya na zuciya, shawarar da aka bada shawarar shine 20-40 MG kowace rana. Idan taro na LDL ya zama ƙasa da 1.94 mmol / L, kuma matakin jimlar cholesrol shine 3.6 mmol / L, to an rage kashi.
A cikin cututtukan koda na koda, shan fibrates, acid nicotinic da Simvastol, adadin da aka ba da shawarar ƙarshen ƙarshen kowace rana bai wuce milligram 10 ba.
Marasa lafiya waɗanda ke shan Amiodarone ko Verapamil ya kamata su dauki Simvastol a cikin adadin har zuwa 20 MG kowace rana.
Tasirin sakamako da hulɗar magani
Yayin aiwatar da magani tare da Simvastol, halayen da yawa marasa kyau zasu iya bunkasa. Don haka, bayan shan magani, ƙwayoyin narkewa sukan rikice, wanda ke bayyana ta zawo, maƙarƙashiya, ɓaɓɓu, ƙwayar ƙwayar cuta, tashin zuciya, tashin zuciya, hepatitis.
Wasu lokuta sakamako masu illa suna shafar tsarin musculoskeletal. Sakamakon wannan shine murƙushe tsoka, myalgia, malaise, myopathy, rhabdomyolysis.
Yayin amfani da simvastatin, bayyanar cututtuka na rashin lafiyan na iya faruwa, irin su urticaria, polymyalgia, lupus, zazzaɓi, vasculitis, angioedema, rheumatoid arthritis, gajeriyar numfashi. Hakanan halayen cututtukan cututtukan fata zasu iya haɓaka - hyperemia da itching na fata, dermatomyositis, daukar hoto, alopecia.
Yin amfani da simvastol na iya yin tasiri ga aikin jijiyoyi:
- Lafiya;
- ciwon kai
- na gefe neuropathy;
- cututtukan asthenic;
- karancin gani a cikin cutar siga;
- rashin bacci
- ƙwayar tsoka;
- paresthesia.
Sakamakon mummunan da ke faruwa bayan ɗaukar Simvastol kuma sun haɗa da raguwa a cikin rashin ƙarfi, gazawar kumburi mara yawa, rashin ƙarfi, ƙyalƙyali mai zafi, da bugun zuciya. Simvastatin kuma zai iya tasiri ga sigogi na dakin gwaje-gwaje, wanda aka nuna ta hanyar thrombocytopenia, karuwa a ESR, eosinophilia.
Game da hulɗa da miyagun ƙwayoyi, yana da kyau sanin cewa miyagun ƙwayoyi suna ƙaruwa da tasiri na maganin rashin ƙarfi, wanda ke kara saurin zubar jini. Sakamakon warkewa na Simvastol yana ƙaruwa tare da aikin haɗin gwiwa tare da ruwan 'ya'yan innabi.
Idan kun ɗauki Allunan tare da Verapamil, cytostatics, Erythromycin, nicotinic acid, Amiodarone, jami'in antifungal, Diltiazem, masu hana masu cutar ta HIV, Telithromycin, Clarithromycin, to, yiwuwar cutar ta myopathy zai karu.
Analogs, sake dubawa da farashin
Akwai magunguna da yawa waɗanda aka yi akan simvastatin. Don haka, zaku iya maye gurbin Simvastol tare da hanyoyi masu zuwa - Simgal, Ariescor, Zovatin, Levomir, Zokor, Simvor, Actalipid.
Sanannen sananne ne na Simvastol shine Avestatin. Wani madadin magani shine Vasilip. Hakanan akwai magunguna da yawa da ake kira kayan aiki masu aiki.
Wadannan magungunan sun hada da Simvastatin Alkaloid / Vero / SZ / Teva / Pfizer / Chaikafarm / Ferein. Sauran analogues da maye gurbin miyagun ƙwayoyi Simvastol - Simvakol, Zorstat, Simlo, Sinkard, Aterostat.
Simvastatin yana da mafi yawan lokuta sake dubawa. Wannan ya faru ne saboda babban ingancin ingancin magani da ƙananan haɗarin haɓaka mara kyau.
Koyaya, mutane masu shan allunan-tushen allunan suna lura cewa magani na iya rage mummunan cholesterol da kashi 20%. Sauran LDL dole ne a cire shi daga jikin ta hanyar maganin abinci.
Wasu marasa lafiya sun ba da rahoton cewa Simvastol ya taimaka musu su guji tiyata. Kuma bayan shafe tsawon watanni shida na jiyya, yanayin zuciya da jijiyoyin jini sun inganta sosai, wanda aka tabbatar da shi ta hanyar gwaje gwaje.
Farashin magungunan ya dogara da sashi. Don haka, Simvastol No. 28 10 MG farashin kimanin 187-210 rubles, kuma Simvastol 20 MG - har zuwa 330 rubles.
Yadda za a rage cholesterol a cikin jini zai gaya wa gwani a cikin bidiyo a wannan labarin.
